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This review analyzes the role of microRNA in cardiovascular risk assessment in familial hypercholesterolemia, highlighting essential findings.
The most common inherited form of dyslipidemia and the main cause of premature cardiovascular disease is familial hypercholesterolemia. This disease is characterized by high levels of low-density lipoprotein cholesterol and, as a consequence, early coronary atherosclerosis and coronary artery disease. Modern research increasingly focuses on the role of small non-coding ribonucleic acids (RNA), in particular microRNA, in the regulation of lipid metabolism and the development of atherosclerotic changes. The aim of this review was to analyze recently published studies describing the potential role of microRNA in assessing cardiovascular risk in patients with familial hypercholesterolemia.
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Mikhailina et al. (2025) studied this question.
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