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This is a Literature Review study.

August 16, 2025Quality in SportOpen Access

Routes of Vitamin B12 Supplementation: Clinical Evidence, Limitations, and Practical Considerations

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Authors

ASAlina SemianiukLublin Oncology Center MSMałgorzata StopaJagiellonian University ESEwa SzczęsnaLublin Oncology Center

Discussion

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Implication

This review assesses vitamin B12 supplementation routes—oral, sublingual, and intramuscular—in addressing deficiency, indicating practical outcomes for patient care.

Key Points

Oral and sublingual vitamin B12 supplementation can be effective for mild deficiencies, improving patient adherence and satisfaction.
Intramuscular administration serves as the gold standard for severe vitamin B12 deficiency with neurological effects—supporting urgent clinical needs.
Malabsorption syndromes and dietary restrictions often lead to vitamin B12 deficiency, necessitating varied supplementation routes based on patient conditions.
Clinical decision-making for vitamin B12 supplementation should consider patient preference, severity, and the logistics of each method.

Cite This Study

Semianiuk et al. (2025) studied this question.

synapsesocial.com/papers/68a366a20a429f797332c759 https://doi.org/10.12775/qs.2025.44.62910

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Implication

This review assesses vitamin B12 supplementation routes—oral, sublingual, and intramuscular—in addressing deficiency, indicating practical outcomes for patient care.

Routes of Vitamin B12 Supplementation: Clinical Evidence, Limitations, and Practical Considerations

Discussion

Member takes

Implication

Key Points

Cite This Study

Routes of Vitamin B12 Supplementation: Clinical Evidence, Limitations, and Practical Considerations

Discussion

Member takes

Implication

Key Points

Cite This Study

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