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August 16, 2025CureusOpen Access

Pretreatment Inflammatory Indices as Predictors of Survival in Endometrial Cancer: A Retrospective Cohort Study From Mexico

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Retrospective cohort study finds systemic inflammation biomarkers affect overall survival in endometrial cancer, suggesting clinical implications.

Poor overall survival is linked to high neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, along with low lymphocyte-to-monocyte ratio in endometrial cancer patients.
Key metrics from 887 women show significant odds ratios for survival correlated to pre-treatment inflammatory indices and other factors.
Multivariable Cox proportional regression analysis included adjustments for factors like FIGO stage, with a median follow-up of about 60 months.
These findings emphasize the potential for inflammatory indices to inform treatment decisions in resource-constrained environments.

Sepúlveda-Rivera et al. (2025) studied this question.

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Retrospective cohort study finds systemic inflammation biomarkers affect overall survival in endometrial cancer, suggesting clinical implications.