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August 16, 2025Monaldi Archives for Chest DiseaseOpen Access

Sonographic diaphragmatic parameters as a predictor of weaning failure in critically ill patients in need of invasive mechanical ventilation: a prospective observational cohort study

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Authors

PKPrathmesh G. KumbharAll India Institute of Medical Sciences BhopalMTManvinder TejpalAll India Institute of Medical Sciences BhopalSKSunaina Tejpal KarnaSanjay Gandhi Post Graduate Institute of Medical Sciences

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Implication

Observational study identifies diaphragmatic thickness and excursion as key weaning predictors in critically ill patients, suggesting clinical utility.

Key Points

  • Pre-intubation diaphragmatic excursion below 10.5 mm predicts complicated weaning outcomes, indicating clinical relevance.
  • Receiver operating characteristic analysis showed an area under the curve of 0.986, demonstrating excellent predictive power with high sensitivity.
  • The study followed 50 patients over 28 days, assessing weaning outcomes based on sonographic diaphragmatic measurements.
  • Significant differences in weaning duration were noted, with patients having lower diaphragmatic excursion needing more intensive care days.

Cite This Study

Kumbhar et al. (2025) studied this question.

synapsesocial.com/papers/68a368710a429f797332d099https://doi.org/10.4081/monaldi.2025.3548
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Real-world inter-observer variability of the sequential organ failure assessment (SOFA) score in intensive care medicine: the time has come for an update: authors’ reply2023 · 11 citations
  2. 2Diaphragm thickening fraction to predict weaning—a prospective exploratory study2017 · 51 citations
  3. 3The Relationship of Diaphragmatic Ultrasound-Based and Manometric Indices With Difficult Weaning in Tracheostomized Patients2024 · 5 citations
  4. 4Assisted mechanical ventilation promotes recovery of diaphragmatic thickness in critically ill patients: a prospective observational study2020 · 49 citations
  5. 5Role of diaphragm ultrasound in weaning mechanically ventilated patients: A prospective observational study2022 · 31 citations