The Urological Subtleties of an Uncommon Encounter with Primary Mucinous Adenocarcinoma of the Urinary Bladder with Review of Literature

Primary mucinous adenocarcinoma (PMA) of the urinary bladder is a rare and aggressive neoplasm, accounting for 0.5-2% of bladder malignancies. We report a case of a 52-year-old male presenting with urinary obstructive symptoms and hematuria. Imaging revealed a bladder mass, and histopathology confirmed muscle-invasive mucinous adenocarcinoma with characteristic mucin pools and signet ring cells. Immunohistochemistry ruled out secondary metastasis, supporting a primary bladder origin, following which the patient underwent radical cystectomy. This case highlights the importance of integrated clinicopathological assessment for accurate diagnosis and management of PMA, contributing valuable insights to this uncommon entity.