Prospective study finds circulating tumor DNA predicts minimal residual disease in urological cancers, suggesting improved prognosis metrics.
BJU InternationalEarly View Research Letter A prospective study of minimal residual disease in urological cancers using circulating tumour DNA Arnav Srivastava, Corresponding Author Arnav Srivastava [email protected] [email protected] orcid.org/0000-0002-9772-1415 Department of Urology, Michigan Medicine, Ann Arbor, MI, USA Correspondence: Arnav Srivastava, 2800 Plymouth Road, Building 16, Ann Arbor, MI 48109, USA. e-mail: [email protected] and [email protected]Search for more papers by this authorDerrian Cooley, Derrian Cooley Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorSteven M. Monda, Steven M. Monda orcid.org/0000-0002-8548-8193 Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorUlka N. Vaishampayan, Ulka N. Vaishampayan Department of Internal Medicine, Hematology/Oncology Division, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorSamuel D. Kaffenberger, Samuel D. Kaffenberger Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorLindsey A. Herrel, Lindsey A. Herrel orcid.org/0000-0003-0221-0784 Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorJeffrey S. Montgomery, Jeffrey S. Montgomery Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorKhaled Hafez, Khaled Hafez Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorAaron M. Udager, Aaron M. Udager orcid.org/0000-0002-8254-5404 Department of Pathology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorZachery R. Reichert, Zachery R. Reichert orcid.org/0000-0003-0356-8796 Department of Internal Medicine, Hematology/Oncology Division, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorD. Bryan Johnson, D. Bryan Johnson Strata Oncology, Ann Arbor, MI, USASearch for more papers by this authorDaniel R. Rhodes, Daniel R. Rhodes Strata Oncology, Ann Arbor, MI, USASearch for more papers by this authorScott A. Tomlins, Scott A. Tomlins Strata Oncology, Ann Arbor, MI, USASearch for more papers by this authorTodd M. Morgan, Todd M. Morgan Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this author Arnav Srivastava, Corresponding Author Arnav Srivastava [email protected] [email protected] orcid.org/0000-0002-9772-1415 Department of Urology, Michigan Medicine, Ann Arbor, MI, USA Correspondence: Arnav Srivastava, 2800 Plymouth Road, Building 16, Ann Arbor, MI 48109, USA. e-mail: [email protected] and [email protected]Search for more papers by this authorDerrian Cooley, Derrian Cooley Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorSteven M. Monda, Steven M. Monda orcid.org/0000-0002-8548-8193 Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorUlka N. Vaishampayan, Ulka N. Vaishampayan Department of Internal Medicine, Hematology/Oncology Division, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorSamuel D. Kaffenberger, Samuel D. Kaffenberger Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorLindsey A. Herrel, Lindsey A. Herrel orcid.org/0000-0003-0221-0784 Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorJeffrey S. Montgomery, Jeffrey S. Montgomery Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorKhaled Hafez, Khaled Hafez Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorAaron M. Udager, Aaron M. Udager orcid.org/0000-0002-8254-5404 Department of Pathology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorZachery R. Reichert, Zachery R. Reichert orcid.org/0000-0003-0356-8796 Department of Internal Medicine, Hematology/Oncology Division, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this authorD. Bryan Johnson, D. Bryan Johnson Strata Oncology, Ann Arbor, MI, USASearch for more papers by this authorDaniel R. Rhodes, Daniel R. Rhodes Strata Oncology, Ann Arbor, MI, USASearch for more papers by this authorScott A. Tomlins, Scott A. Tomlins Strata Oncology, Ann Arbor, MI, USASearch for more papers by this authorTodd M. Morgan, Todd M. Morgan Department of Urology, Michigan Medicine, Ann Arbor, MI, USASearch for more papers by this author First published: 13 August 2025 https://doi.org/10.1111/bju.16890Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookxLinkedInRedditWechatBluesky No abstract is available for this article. References 1Brown JR, Sonpavde GP, Calaway A, Barata PC. Circulating tumor DNA to assess minimal residual disease: versatile, but how valuable? 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