Autoimmune‐Like Hepatitis Following Hepatic Graft‐Versus‐Host Disease in an Allogenic Hematopoietic Cell Transplant Recipient

One of the major complications following hematopoietic cell transplantation (HCT) is the occurrence of graft‐versus‐host disease (GVHD). The liver is a target organ in both acute and chronic GVHD. Histologically, there are two distinct forms of hepatic involvement by GVHD, namely cholestatic (classical) and hepatic. Autoimmune‐like hepatitis has been reported as a late complication of HCT with some considering it to be a variant of hepatic GVHD. However, there are no reports of hepatic form of GVHD and autoimmune‐like hepatitis in the same patient post‐HCT. Herein, we report a patient who initially developed hepatic GVHD followed by autoimmune‐like hepatitis.