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August 17, 2025Frontiers in Cell and Developmental BiologyOpen Access

Metabolic reprogramming and immunosenescence in colorectal cancer: mechanisms and therapeutic implications

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Authors

JZJun ZhuShanghai Medical College of Fudan UniversityKSKuan ShenChongqing UniversityQSQiang SuMinistry of Natural Resources

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Implication

This review highlights the roles of metabolic reprogramming and immunosenescence in colorectal cancer, suggesting targeted therapies for better outcomes.

Key Points

  • Metabolic reprogramming and immunosenescence contribute to immune escape in colorectal cancer, complicating treatment.
  • Recent studies indicate that these mechanisms play crucial roles in tumor development and resistance to therapies.
  • Systematic review of the interplay between immune responses and tumor microenvironment highlights potential therapeutic strategies.
  • Understanding these processes may lead to more precise treatment approaches for colorectal cancer patients.

Cite This Study

Zhu et al. (2025) studied this question.

synapsesocial.com/papers/68a36c1a0a429f797332f6d2https://doi.org/10.3389/fcell.2025.1662464
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