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August 17, 2025Journal of Cancer Metastasis and TreatmentOpen Access

A ferroptosis-based gene signature for relapse prediction in prostate adenocarcinoma

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Authors

LWL.Y. WangNational Taiwan UniversityMWMofei WangWestern UniversityMFMei-Yin FanUnion Hospital

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Implication

The prognostic index predicts prostate cancer outcomes, suggesting ferroptosis and immune factors influence recurrence.

Key Points

  • The FRG index predicts prostate cancer recurrence based on immune infiltration and molecular pathways, enhancing clinical utility.
  • It showed significant correlation with advanced cancer stages and higher prostate-specific antigen levels, indicating severe prognosis.
  • Observational analysis used multiple datasets to validate the FRG prognostic model linked with clinicopathological parameters.
  • Highlights the potential clinical effectiveness of doxorubicin for recurrent prostate cancer, opening new immunotherapeutic strategies.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68a36c1a0a429f797332f753https://doi.org/10.20517/2394-4722.2025.73
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