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August 17, 2025International Journal of Molecular SciencesOpen Access

Refining Prognostic Factors in Adult-Onset Multiple Sclerosis: A Narrative Review of Current Insights

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Authors

TGTommaso GuerraMCMassimiliano CopettiMAMariaclara Achille

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Overview

Narrative review investigates prognostic factors and biomarkers impacting disease progression in MS, suggesting improved management strategies.

Key Points

  • Identifying reliable prognostic biomarkers is crucial for improving long-term outcomes in people with multiple sclerosis.
  • The review highlights baseline clinical and neuroimaging factors that can predict disease progression and irreversible disability.
  • Assessment of emerging biomarkers of smoldering disease is emphasized to enhance prognostic accuracy in MS patients.
  • Integrating prognostic tools and risk scores may significantly support therapeutic decision-making in clinical practice.

Cite This Study

Guerra et al. (2025) studied this question.

synapsesocial.com/papers/68a36c210a429f797332fbb8https://doi.org/10.3390/ijms26167756
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early Prognostic Factors in Multiple Sclerosis: Clinical and Therapeutic Implications2026
  2. 2Prognostic factors in paediatric-onset multiple sclerosis: a narrative review2026
  3. 3Determinants and Biomarkers of Progression Independent of Relapses in Multiple Sclerosis2024 · 101 citations
  4. 4The Crossroads of Neuroinflammation and Biomarkers in Multiple Sclerosis: A Systematic Review2026 · 4 citations
  5. 5Genetic Prognostic Factors in Multiple Sclerosis: Key Discoveries and Unmet Needs2026