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August 17, 2025Regenerative BiomaterialsOpen Access

3D-printed Strontium-incorporated β-TCP Bioceramic Triply Periodic Minimal Surface Scaffolds with Enhanced Angiogenic and Osteogenic Properties

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Authors

YSYanbo ShanYBYang BaiLZLisheng Zhao

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Overview

Incorporating strontium into beta-TCP scaffolds improves angiogenesis and osteogenesis, indicating a promising biomaterial for bone healing.

Key Points

  • The scaffold significantly improved bone healing in rat femoral condylar defects, indicating enhanced regenerative properties.
  • In vitro assays showed a dose-dependent stimulation of osteogenic differentiation and mineralization in MC3T3-E1 cells.
  • Using digital light processing, a biomimetic TPMS structure was engineered with optimal 10 mol% strontium incorporation.
  • This approach highlights the potential for developing advanced biomaterials to address challenges in bone regeneration.

Cite This Study

Shan et al. (2025) studied this question.

synapsesocial.com/papers/68a36c270a429f797332fd7dhttps://doi.org/10.1093/rb/rbaf080
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