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Case Report of Isolated Aortic Valve AL-amyloidosis Following Aortic Valve Replacement

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Case report reveals isolated aortic valve al-amyloidosis in aortic stenosis, indicating distinct pathology from ATTR.

Aortic valve al-amyloidosis was identified post-surgery, without myocardial or systemic involvement.
The study uncovered amyloid deposits classified as the AL subtype, highlighting a diagnostic challenge.
Pathology analysis indicated a need for amyloid typing to differentiate from transthyretin amyloidosis.
Multidisciplinary team deferred further treatment due to the patient's clinical stability and isolated valve involvement.

Choudhury et al. (2025) studied this question.

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