Synthesis of axially chiral 5,5’-substituted 2,2’-bipyridine ligands andtheirapplication in palladium-catalyzed asymmetric oxidative [2+2] annulation

A series of axially chiral 5,5’-substituted 2,2’-bipyridine ligands featuring tunable properties has been synthesized. They have been successfully applied to palladium-catalyzed asymmetric oxidative [2+2] annulation of arylboronic acids and alkenes,...