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August 17, 2025The Journal of Medical ResearchOpen Access

Correlation between Phenotypic Hypermucoviscosity and Antibiotic Resistance in Klebsiella pneumoniae

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Authors

KSKhaja Mohiddin ShaikGTGeetanjali TupakulaBNBathala Nagasrilatha

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Overview

Cross-sectional analysis links hypermucoviscosity with enhanced antibiotic resistance in Klebsiella pneumoniae isolates, suggesting urgent screening needs.

Key Points

  • Hypermucoviscosity in Klebsiella pneumoniae correlates with increased antibiotic resistance, particularly to gentamicin and imipenem.
  • Among 196 isolates, 19.39% showed the hypermucoviscous phenotype, primarily from respiratory sources.
  • Analysis involved clinical isolates tested for hypermucoviscosity using the string test and antibiotic susceptibility via disc diffusion.
  • The rising incidence of drug-resistant hypermucoviscous strains underscores the importance of screening and stewardship.

Cite This Study

Shaik et al. (2025) studied this question.

synapsesocial.com/papers/68a36dec0a429f7973331c2dhttps://doi.org/10.4103/jmr.jmr_25_25
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