Clinical pattern of nephrotic syndrome and treatment response in children

The pattern of presentation, laboratory features, complications and initial therapeutic response in cases of nephrotic syndrome in 1 to 10-year-old children is of interest. A prospective observational investigation was performed on 164 participants for eighteen months. It was carried out in the Pediatric Ward and Outpatient Department from the Department of Pediatrics, Netaji Subhash Chandra Bose Medical College and Hospital, Jabalpur, Madhya Pradesh. It was found that nephrotic syndrome was most common in males, with edema being a universal symptom and a large proportion presented with relapse. Most children responded to the use of steroids, although minorities were steroid-resistant or dependent.