Analysis reveals that interstitial lung abnormalities significantly lower overall survival in patients with lung cancer, suggesting they may indicate worse long-term outcomes.
Key Points
The presence of interstitial lung abnormalities is linked to a significant decrease in overall survival after lung cancer surgery, and those with ILAs face increased risk of mortality.
5-year overall survival rates were markedly lower in patients with ILAs, at 82.5% compared to 93.4% in those without, indicating a major prognostic impact.
Analysis included 1711 patients with pathologic stage I non-small-cell lung cancer, employing deep learning texture analysis for quantification of ILAs.
Mortality from causes other than lung cancer was significantly higher in the ILA group, emphasizing the broader health implications of these abnormalities.