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Synthesis of 2-phenyl-4h-benzo[d][3,1]-oxazin-4-one complexes with Hg(II) and Sn(II) ions, showing promising antimicrobial activity.
A ligand PHBO (2-Phenyl-4H-benzo[d][3,1]-oxazin-4-one) is synthesized from the condensation of anthranilic acid, benzoyl chloride and acetic anhydride. A new PHBO complexes derived from 2-Phenyl-4H-benzo[d] [3,1]-oxazin-4-one with Hg (II) and Sn (II) ions. The prepared metal chelates was characterized by IR, NMR, TGA-DTA, XRD, Elemental analysis and molar conductance measurements. The PHBO ligand and their metal chelates have been tested for their antimicrobial activity using Broth Dilution Method and the results were discussed.
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Ade et al. (2025) studied this question.
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