Prevention of cardiovascular diseases of technogenic and social genesis through nutrition modification

The study of the aetiology and pathogenesis of diseases caused by a lack or excess of certain substances in the body is a key area of research in the prevention of nutritional and nutritionally dependent diseases. Scientific evidence has demonstrated the impact of dietary quality and calorie content on physical and mental health, with certain substances regulating the course of biochemical and adaptive reactions. Aim. To scientifically substantiate measures of nutritional prevention of heart and vascular diseases caused by the effects of exogenous factors of technogenic and social origin through dietary modification. Materials and Methods. To achieve the goal, the following methods were used: bibliosemantic analysis method (study of professional modern special scientific and methodological and international literature on the problem under study); method of theoretical analysis and generalization of data on the problem of health and nutrition of the working-age population living in the occupied territories of the Kyiv region; provisions of applied and medical statistics regarding the planned studies. The source of initial information for epidemiological research and analysis was materials of own observations and data from the State Institution Ukrainian Centre for Information Technology and the National Registry of the Ministry of Health of Ukraine (DRU). The results of the field studies were statistically processed using Student’s t-test criterion for independent samples, unlicensed Microsoft Excel software and with preliminary testing of the hypothesis of the normal law of distribution of a random variable according to the Kolmogorov-Smyrnov criterion [13]. All results are presented in the quantities accepted by the International System of Units (SI) [14]. Results and Discussion. Social disturbances, martial law and various psycho-emotional overloads in combination with poorquality, unbalanced nutrition form pre-pathological situations, which over the time lead to a permanent disruption of the functioning of organs and body systems. The conditions that developed during the occupation exacerbated the problem of not only pre-morbid conditions, but also of mortality among the population of the occupied territories. Conclusions. The primary indicator of potential disorders is the state of the cardiovascular system, which exhibits a rapid response to the impact of various stress factors, including psycho-emotional factors. The range of products consumed can significantly affect the formation and development of disorders in the body. An insufficient amount of essential compounds affects the processes of metabolism, regeneration and renewal of damaged cells of the most vulnerable organs and systems. To prevent the development of cardiovascular diseases of alimentary genesis, it is necessary to quickly and effectively replenish the loss of irreplaceable ingredients, which is possible with their timely intake with food. The most rational means of preventing damage to the cardiovascular system due to poor-quality, unbalanced, untimely nutrition are substantiated recommendations. They take into account a sufficient variety of consumed products of both plant and animal origin, and also contribute to the restoration of affected structures and will level the consequences of population stress due to occupation. Reducing cardiovascular disease levels through diet alone is of great therapeutic and preventive importance.