Basic principles of field trials for the residues determination of plant protection products in crops

The Decision of the National Security and Defence Council of Ukraine ‘On Measures to Improve Chemical Safety in Ukraine’, enacted by Presidential Decree No. 104/2021, provides for the improvement of requirements for the procedure for placing plant protection products (PPPs) on the market, taking into account European approaches and international practices. An important part of this procedure is the study of PPPs residues to establish health standards and ensuring chemical safety of the use of food raw materials and consumption of food products obtained with the use of PPPs. Aim. To summarize the basic principles and scientific substantiation of approaches to improving the research scheme for determining the residues of active substances (a.s.) of PPPs in agricultural crops grown with their application. Materials and Methods. Regulatory and legal acts governing the registration of PPPs, regulatory, scientific and methodological documents in force in Ukraine and the EU on the organization of research on the a.s of PPPs residues in crops treated with PPPs. Expert and analytical methods. Results and Conclusions. The basic principles and scientifically based approaches to optimizing the scheme of field trials to determine the residues of PPPs in crops grown with their use are summarized. When testing PPPs, the properties of the active substances and the crop under study should be taken into account, the real conditions and peculiarities of PPPs application should be reproduced, which may lead to the detection of the maximum possible active substances of PPPs residues in the agricultural raw materials under study after PPPs application. The use of the proposed approaches to research planning will ensure optimization of the procedure for field trials of PPPs, formation of a sufficient set of data, as well as further adequate interpretation of the results obtained to substantiate the health standards - maximum residues levels (MRL) in agricultural raw materials obtained with the use of PPPs and waiting periods for harvesting crops in Ukrainian agriculture.