Urgency of harmonizing domestic pesticide analysis methods in agricultural and food raw materials, food products, feed and environmental objects according to the requirements of the European union, organization for economic cooperation and development. Part 1. General Aspects of Pre- and Post-Registration Methods for Pesticide Residue Analysis

Aim. To review the general aspects of the development and use of pre- and post-registration methods for pesticide residue analysis in the European Union (EU) and the Organisation for Economic Cooperation and Development (OECD) in food products, animal feed, and environmental objects, and to provide proposals for the development and implementation of domestic regulations in this field. Materials and Мethods. Analytical review of the EU and OECD guidelines, legislative documents, and scientific publications devoted to the development and use of pesticide residue analysis methods for obtaining data to assess the impact of pesticides on human health (risk assessment) and the environment, for establishing maximum residue limits (MRLs) to ensure compliance with the established MRLs and monitoring objectives. Ukrainian legislative documents regulating the development and use of pesticide residue analysis methods for laboratory control need significant revision to align with the EU and OECD requirements. Conclusions. Proposals have been formulated for the creation of domestic guidelines for the development and use of pesticide residue analysis methods for risk assessment, pre- and post-registration control, and monitoring objectives based on the EU and OECD guidelines.