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August 21, 2025The International Journal of NeuropsychopharmacologyOpen Access

Cannabidiol Mitigates Cognitive Deficits in a Mouse Model of Alzheimer’s Disease

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Authors

YCYC ChenYHY-H HsiaoSHSusan C. Hu

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Overview

Observational analysis shows improved cognitive function in a mouse model of Alzheimer's disease, indicating CBD's therapeutic potential.

Key Points

  • CBD treatment improved cognitive performance in 3xTg-AD mice, demonstrating significant benefits over vehicle injections.
  • Mice receiving CBD showed increased time in target zones of the Morris water maze, highlighting enhanced cognitive function.
  • Behavioral tests were conducted using the Morris water maze, Object Location Test (OLT), and Open Field Test (OFT) across a three-week intervention.
  • These results suggest that CBD may offer a new therapeutic application in managing Alzheimer's disease symptoms.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68a6fb9e5502675167ba9a12https://doi.org/10.1093/ijnp/pyaf052.192
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