Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 25, 2025

Cannabidiol improves short-term memory in a Streptozotocin-induced animal model of Alzheimer’s disease

View Full Paper
Ask AI
Bookmark
Share

Authors

GPGabrielle Christine PereiraUniversidade Federal de São PauloVSVanessa Lima do Nascimento SilvaUniversidade Federal de Santa MariaBSBeatriz Soares‐SilvaInstituto de Saúde

Discussion

Loading...

Member takes

Implication

Experimental model shows cannabidiol improves cognitive function in Alzheimer's disease, indicating it may have neuroprotective benefits.

Key Points

  • CBD treatment significantly improved short-term memory in rats with Alzheimer's disease.
  • Streptozotocin induced cognitive deficits and increased amyloid-beta levels in treated animals.
  • Wistar rats received CBD over 14 days, demonstrating its potential neuroprotective effects.
  • Findings support cannabidiol's role as a candidate for treating neurodegenerative diseases.

Cite This Study

Pereira et al. (2025) studied this question.

synapsesocial.com/papers/689a0627e6551bb0af8ce0f0https://doi.org/10.21203/rs.3.rs-7197783/v1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antidepressant, anxiolytic and procognitive effects of rivastigmine and donepezil in the chronic mild stress model in rats2016 · 68 citations
  2. 2Psychiatric Symptoms Vary With the Severity of Dementia in Probable Alzheimer's Disease2003 · 278 citations
  3. 3Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report2010 · 541 citations
  4. 4The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas2001 · 2,883 citations
  5. 5Melatonin reduces β-amyloid accumulation and improves short-term memory in streptozotocin-induced sporadic Alzheimer’s disease model2023 · 49 citations