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Mathematical models of human breathing regulation and gas exchange during physical exercises

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Breathing regulation changes during physical exercise involve complex interactions between respiratory and cardiovascular systems.
Alveolar gas composition stability transitions from rest to exercise indicates coordinated responses, requiring advanced modeling for understanding.
Existing models primarily focus on deviations from homeostasis but do not adequately explain rapid responses during physical activity.
Understanding chemoreflex interactions can improve predictions of ventilatory responses under varied gas compositions.

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Review of mathematical models highlights the cardiorespiratory system's response during physical exercises, suggesting new principles may apply.

Ermolaev et al. (2025) studied this question.

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Review of mathematical models highlights the cardiorespiratory system's response during physical exercises, suggesting new principles may apply.