This research demonstrates a validated RP-HPLC method for quantifying rupatadine in pharmaceuticals, indicating reliability and accuracy for drug analysis.
Key Points
The method achieved linearity with a correlation of 1.0000 and a range of 17.04-85.20 µg/ml for rupatadine.
Percentage recovery of rupatadine was between 99.08 and 100.25, demonstrating high accuracy.
The reverse phase high performance liquid chromatography method offers a sensitive detection limit of 0.63 µg/ml for rupatadine.
Results suggest the RP-HPLC method is robust, accurate, and suitable for the analysis of rupatadine in pharmaceuticals.