Giant Condyloma Acuminatum of Buschke-Lowenstein: A Case Report

Buschke-Löwenstein tumor is a rare, slow-growing tumor that may arise from a pre-existing condylomatous lesion and has exophytic, cauliflower-like, or papillomatous growth pattern. These tumors are associated with low-risk human papillomavirus infection, most commonly types 6 or 11. They predominantly occur in men in the anogenital region, and are associated with immunodeficiency. The treatment is controversial, but the greatest success has been observed with “cold knife” surgical resection with clear margins. We present the case of a 42-year-old woman with a tumor in the anogenital region that grew progressively over the course of 6 months. The giant condyloma acuminatum covered most of the labia majora of the vulva in a continuous pattern. Multifocal condylomas were observed both at the vaginal introitus and at the lateral aspect of the primary tumor. The patient was tested and had no other sexually transmitted infections. After adequate preoperative preparation, a wide partial vulvectomy was performed. The postoperative course was uneventful. Adequately planned surgery remains a treatment of choice for patients with giant condylomas.