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January 1, 2025RSC AdvancesOpen Access

A dual-type I/II NIR photosensitizer for effective cancer photodynamic therapy with enhanced ROS generation

Shuhua Cao Yuchang Liu Xi–Shi Tai Li Shen Hekai Yang Fahui Li Binglin Sui Pengju Ma Lingxuan Zhu Bin Gao Anlin Wang Mohammad Azam

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Key Points

Enhanced ROS generation resulted from the newly synthesized dual-type I/II NIR photosensitizer, aiding cancer treatment.
The novel photosensitizer showed marked effectiveness in photodynamic therapy (PDT) against tumors during tests.
Synthesis of the dual-type I/II NIR photosensitizer was followed by performance assessments under specific conditions.
These findings highlight potential advancements in cancer therapies, warranting further exploration into ROS mechanisms.

Implication

A novel dual-type I/II NIR photosensitizer improves ROS generation in cancer, suggesting enhanced photodynamic therapy efficacy.

Abstract

A dual-type I/II NIR photosensitizer was synthesized for effective PDT of tumors with enhanced ROS generation.

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Cite This Study

Cao et al. (2025) studied this question.

synapsesocial.com/papers/68af4322ad7bf08b1ead1dc0 https://doi.org/10.1039/d5ra05267j

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