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August 18, 2025Journal of NanobiotechnologyOpen Access

The potential of plant-derived vesicles in treating periodontitis and associated systemic diseases: current advances and future directions

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Authors

ZLZongshuai LiuWuhan UniversityYGYonglin GuoShanghai Jiao Tong UniversityYDYifei DengWuhan University

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Overview

This review demonstrates that plant-derived vesicles can improve the treatment of periodontitis and associated diseases, highlighting their ability to regulate inflammatory responses.

Key Points

  • Plant-derived vesicles show promise in treating periodontitis, suggesting innovative strategies for oral health.
  • Recent findings indicate that these vesicles can regulate inflammatory responses and promote tissue regeneration.
  • This assessment incorporates current research advances and outlines challenges in applying plant-derived vesicles in clinical settings.
  • Understanding production limitations and enhancing mechanistic knowledge are essential for future therapeutic applications.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68af453aad7bf08b1ead29d4https://doi.org/10.1186/s12951-025-03651-0
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  1. 1Plant-derived vesicle-like nanoparticles: current applications in systemic conditions and future horizons in oral diseases2026
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  3. 3Exploring new avenues of health protection: plant-derived nanovesicles reshape microbial communities2024 · 6 citations
  4. 4The Promise and Challenges of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Periodontal Disease2026
  5. 5Periodontitis and extracellular vesicles: Emerging roles in inflammation, tissue destruction and systemic crosstalk2026