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August 18, 2025Open Access

Endoscopic Endonasal Approach for Rare Skull Base Pathologies: Insights from a Neurosurgical Perspective

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Authors

AEAtakan EmengenBahçeşehir UniversityAGAykut GökbelBahçeşehir UniversityEYEren YılmazIstinye University

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Implication

Retrospective analysis reveals surgical challenges and complications in rare skull base tumors, indicating the need for tailored strategies.

Key Points

  • Gross total resection was achieved in 68% of cases involving rare skull base pathologies, highlighting surgical effectiveness.
  • Unexpected vascularity and fibrotic adhesions presented intraoperative challenges that complicated the surgical process.
  • A total of 41 patients with rare skull base pathologies were evaluated, revealing significant variability in complications and outcomes.
  • Tailored adjuvant treatments led to durable disease control for most patients in this challenging surgical context.

Cite This Study

Emengen et al. (2025) studied this question.

synapsesocial.com/papers/68af453fad7bf08b1ead2c65https://doi.org/10.20944/preprints202508.1210.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Endoscopic Endonasal Approach for Rare Skull Base Pathologies: Insights from a Neurosurgical Perspective2025
  2. 2Endoscopic Endonasal Skull Base Surgery: Analysis of the Results in the Author’s Initial 200 Cases2024 · 1 citations
  3. 3Clinical Outcome of Extended Endoscopic Endonasal Transclival Approach for Skull Base Lesions2026
  4. 4３．Endoscopic Approach to the Skull Base and Adjacent Organs2024
  5. 5Pneumocephalus and delayed hydrocephalus following endoscopic endonasal biopsy of skull base lesion: diagnostic pitfalls and the role of immunohistochemistry.2026