Palladium-catalyzed cycloaddition generates diverse spirocyclic compounds, suggesting broad applicability in synthesis.
A palladium-catalyzed [3+2] cycloaddition reaction of vinyl methylene cyclic carbonates with pyrrolidinones was developed. This protocol demonstrates remarkable versatility, enabling the facile construction of diverse [5,5]-spirolactam scaffolds in excellent yields...
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Liu et al. (2025) studied this question.
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