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This is a Observational study (also classified as: In Vitro Study).

August 17, 2025Scientific ReportsOpen Access

Cortical modulation of resting state BOLD signals in white matter

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Resting state BOLD signals in white matter are modulated by spontaneous cortical activity, indicating significant neural communication.
Cortical networks linked to basic functions show stronger contributions to correlated fluctuations in white matter, highlighting functional organization.
Measurements reveal distinct spatial patterns among cortical networks affecting white matter BOLD signals, indicating varied influences on neural signaling.
Findings correlate the modulation of BOLD signals to the myelination level of cortical networks, suggesting a link between structure and function.

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Analysis reveals how cortical networks modulate resting state BOLD signals in white matter, suggesting myelination influences activity.

Ding et al. (2025) studied this question.

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