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August 16, 2025

Real-world waitlist randomised controlled trial of gameChange VR to treat severe agoraphobic avoidance in patients with psychosis: a study protocol.

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Authors

DFDaniel FreemanJJJulia JonesEPEloise Prouten

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Overview

Real-world trial assesses gameChange VR's impact on agoraphobic avoidance in patients with psychosis, suggesting potential for routine NHS use.

Key Points

  • Patients in the trial will show a reduction in agoraphobic avoidance at 26 weeks, indicating gameChange VR's effectiveness.
  • In prior studies with 346 patients, those with severe issues showed the greatest improvements in their fears.
  • Randomised controlled trial comparing gameChange VR therapy plus usual treatment to a waitlist control group.
  • The findings may support updates to National Institute for Health and Care Excellence guidance on mental health interventions.

Cite This Study

Freeman et al. (2025) studied this question.

synapsesocial.com/papers/68af474ead7bf08b1ead3caehttps://doi.org/10.1136/bmjopen-2025-104636
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Feasibility trial of the virtual reality application gameChange in a Norwegian psychosis participant group2026 · 1 citations
  2. 2An Automated Virtual Reality Cognitive-Behavioural Preventive Intervention for Adults with Agoraphobic Symptoms: A Randomized Controlled Trial of Adapted gameChange in Hong Kong2025
  3. 3Virtual reality and social avoidance: an exploratory study of acceptance, and feasibility in an inpatient secure environment2024 · 2 citations
  4. 4Acceptability, feasibility, and preliminary evaluation of an animated VR game for reducing mental health stigma in health-care students and trainees: a mixed-method study2024
  5. 5Enabling accessible social anxiety care: a pilot study of a virtual reality serious game in a resource-constrained public health setting2026