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August 1, 2025

Progress on small non-coding RNAs in male reproductive development and intergenerational inheritance.

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Authors

YSYuqian ShiJMJianfeng MaSCSiyu Chen

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Overview

Review highlights small non-coding RNAs' roles in spermatogenesis and gene expression, suggesting links to male infertility.

Key Points

  • Small non-coding RNAs are critical for gene expression and germ cell development, influencing male reproduction.
  • Abnormal levels of small non-coding RNAs are notably associated with male infertility, emphasizing their importance.
  • Research indicates that environmental factors affect the epigenetic modification of sperm, impacting future generations.
  • Understanding the functions of small non-coding RNAs may offer new strategies for addressing male infertility issues.

Cite This Study

Shi et al. (2025) studied this question.

synapsesocial.com/papers/68af474ead7bf08b1ead3cb0https://doi.org/10.16288/j.yczz.24-335
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Small RNA molecules in the regulation of spermatogenesis2009 · 160 citations
  2. 2Spermatogenesis Beyond DNA: Integrated RNA Control of the Epitranscriptome and Three-Dimensional Genome Architecture2026 · 3 citations
  3. 3MicroRNAs in spermatogenesis dysfunction and male infertility: clinical phenotypes, mechanisms and potential diagnostic biomarkers2024 · 48 citations
  4. 4Identification of Likely Novel piRNA Sequences in Human Testis Tissue and Bioinformatics Analysis2024
  5. 5MicroRNAs in Male Fertility2024 · 10 citations