Carbon Quantum Dots-Based Fluorometric Detection of Nitrosamines Impurities in Active Pharmaceutical Ingredients

Loganathan Gayathri; Pirangi Srikanth; Khaja Moinuddin Shaik; Sukhendu Nandi

doi:10.1039/d5na00490j

January 1, 2025Nanoscale AdvancesOpen Access

Carbon Quantum Dots-Based Fluorometric Detection of Nitrosamines Impurities in Active Pharmaceutical Ingredients

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Key Points

The fluorometric detection method identifies nitrosamines effectively, enhancing safety in pharmaceuticals.
Results indicate that the rapid detection method reduces the risk of genotoxic impurities in drug products.
The approach utilizes carbon quantum dots for a sensitive detection of impurities in active pharmaceutical ingredients.
This method highlights the urgent need for improved safety measures in the pharmaceutical industry.

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Implication

Fluorometric detection of nitrosamines in active pharmaceutical ingredients reveals rapid screening potential.

Abstract

Nitrosamines are genotoxic, mutagenic impurities and widely encountered in the global landscape of the pharmaceutical industry. There is a need for rapid detection of nitrosamines in a pharmaceutical product. Here...

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Cite This Study

Gayathri et al. (2025) studied this question.

synapsesocial.com/papers/68af475aad7bf08b1ead4204 https://doi.org/10.1039/d5na00490j

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Carbon Quantum Dots-Based Fluorometric Detection of Nitrosamines Impurities in Active Pharmaceutical Ingredients

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Carbon Quantum Dots-Based Fluorometric Detection of Nitrosamines Impurities in Active Pharmaceutical Ingredients

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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