August 16, 2025VaccinesOpen Access

Immune Response to Childhood Vaccination in Vertically Infected People Living with HIV: A Long-Term Evaluation

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Authors

AZAnnachiara ZinUniversity of Padua EBElisa BarbieriUniversity of Padua GBGiulia BrigadoiUniversity of Padua

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Implication

Observational study evaluates immune response to childhood vaccines in vertically infected individuals with HIV, suggesting the need for timely boosters.

Key Points

Vaccine-induced immunity was suboptimal, with protective levels declining over time after childhood immunization.
At two years, seroprotection rates varied from 54% to 87%, declining below 30% for most vaccines by twenty years, indicating poor long-term immunity.
Cross-sectional observational study assessed antibody titers against multiple vaccines using serological testing and medical records.
Findings support the need for tailored immunization strategies with regular monitoring to maintain protection in this high-risk group.

Cite This Study

Zin et al. (2025) studied this question.

synapsesocial.com/papers/68af4760ad7bf08b1ead445e https://doi.org/10.3390/vaccines13080871

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Implication

Observational study evaluates immune response to childhood vaccines in vertically infected individuals with HIV, suggesting the need for timely boosters.

Immune Response to Childhood Vaccination in Vertically Infected People Living with HIV: A Long-Term Evaluation

Discussion

Member takes

Implication

Key Points

Cite This Study

Immune Response to Childhood Vaccination in Vertically Infected People Living with HIV: A Long-Term Evaluation

Discussion

Member takes

Implication

Key Points

Cite This Study

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