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August 19, 2025MetabolomicsOpen Access

Association of the HDL lipidome with HDL traits before and after exercise training: HERITAGE family study

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Limited effects of exercise training on HDL lipidome in healthy adults, with changes noted across sex groups.
The study identified 341 lipid species, analyzing their abundance before and after a 20-week training period.
Utilizing lipidomic analysis, differences in HDL lipids were observed, highlighting the need for further research.
Findings may indicate that HDL lipid composition should be considered when examining cardiovascular health and exercise effects.

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Analysis shows limited impact of exercise on HDL lipid classes in 154 adults, suggesting sex-specific variations.

Dev et al. (2025) studied this question.

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