Pd-catalyzed benzannulation creates naphthoferrocene derivatives, suggesting efficient PAH synthesis.
A Pd‐catalyzed formal [4 + 2] benzannulation of 1‐ferrocenyl‐2‐bromobenzene with diarylacetylenes involving C─C coupling/C─H functionalization processes are developed, which provides a straightforward access to various substituted naphtho‐ferrocenes. This methodology offers a novel and efficient approach to produce polycyclic aromatic hydrocarbons (PAHs). The preliminary investigation shows the chiral phosphine ligand N ‐Me‐PC‐Phos has great potential in the asymmetric synthesis of planar naphtho‐ferrocene derivatives.
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He et al. (2025) studied this question.
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