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August 19, 2025Diabetology & Metabolic SyndromeOpen Access

Comparative analysis of 16 baseline obesity and lipid-related indices for cardiovascular disease risk prediction in adults with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide prospective cohort study

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Authors

YPYilin PanCapital Medical UniversityBDBeibei DuUnion HospitalLFLong FengCapital University

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Implication

Cohort study compares 16 obesity and lipid-related indices for predicting cardiovascular disease risk in adults with CKM syndrome, suggesting TyG-WC is most predictive.

Key Points

  • The study found that a higher triglyceride-glucose waist circumference index corresponds to a 15% higher cardiovascular disease risk.
  • During the 6-year follow-up, there were 1,134 new cardiovascular disease cases identified in the cohort.
  • A nationwide prospective cohort study utilized data from CHARLS, including 5,782 participants aged 45 and older.
  • These obesity and lipid-related indices can effectively help assess cardiovascular disease risk in the CKM syndrome population.

Cite This Study

Pan et al. (2025) studied this question.

synapsesocial.com/papers/68af494dad7bf08b1ead4c23https://doi.org/10.1186/s13098-025-01919-x
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