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August 20, 2025Epigenetics & ChromatinOpen Access

The epigenetic circle: feedback loops in the maintenance of cellular memory

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Authors

MTMarko TomljanovićUniversity of International Business and EconomicsCMCita Hanif MuflihahMuhammadiyah University of SurakartaDRDejan Rajkovski

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Implication

This review summarizes how feedback loops sustain epigenetic memory in cells across divisions, indicating their crucial role in gene expression.

Key Points

  • Maintaining epigenetic memory depends on feedback loops that persist through cellular divisions.
  • Key mechanisms include cis- and trans- feedback loops, supporting gene expression and cell fate stability.
  • This review assesses current knowledge and challenges in understanding the stability of epigenetic memory.
  • Insights from this review may drive future research in epigenetic mechanisms and cellular processes.

Cite This Study

Tomljanović et al. (2025) studied this question.

synapsesocial.com/papers/68af4959ad7bf08b1ead5445https://doi.org/10.1186/s13072-025-00621-6
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