Study of Sorption of Chlortetracycline Hydrochloride on Zirconium-Based Metal–Organic Framework Followed by Determination by UV-Vis Detection

The reaction of zirconium tetrachloride with 2-amino-1,4-benzenedicarboxylic acid in N,N-dimethylformamide with the addition of HCl leads to the formation of zirconium 2-amino-1,4-benzenedicarboxylate. Zirconium 2-amino-1,4-benzenedicarboxylate was characterized by elemental analysis, infrared spectrometry, X-ray diffraction, scanning electron microscopy, and volumetric nitrogen adsorption/desorption. The sample has a constant porosity with an average pore diameter of 7.97 nm and both microporous and mesoporous structure with a large surface area (820 m2/g) corresponding to the type IV adsorption. Zirconium 2-amino-1,4-benzenedicarboxylate was used for solid-phase extraction (SPE) of chlortetracycline hydrochloride from the aqueous solution. The obtained results confirmed the possibility of using the proposed analytical technique as a new, convenient approach to the extraction of chlortetracycline hydrochloride from industrial or other wastewaters, where such substance is contained in insignificant concentrations and its determination requires expensive and complex equipment. In the future, this method can be used not only for the effective removal of pollutants from industrial wastewater with subsequent regeneration of the sorbent, but also as a sample-preparation method for concentrating chlortetracycline hydrochloride from dilute solutions with its subsequent elution and analysis by available methods, for example, spectrophotometry, since the limit of detection is 0.06 mg/L. Experimental data are described by the isotherm of SPE (R2 = 0.998–0.999) and show the ability of zirconium 2-amino-1,4-benzenedicarboxylate to extract up to 578 mg/g of sorbent at 5 °C under optimal conditions.