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August 20, 2025Theoretical and Natural ScienceOpen Access

Gut Microbiota Dysbiosis and Depression: Pathological Mechanisms and the Therapeutic Potential of Probiotic Interventions

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Authors

YWYifan Wang

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Overview

Review evaluates gut microbiota dysbiosis in depression, highlighting probiotic potential and therapeutic implications.

Key Points

  • Probiotic supplementation improves depressive symptoms and restores neuroplasticity biomarkers, enhancing overall treatment outcomes.
  • Major depressive disorder affects global health, with existing treatments often providing incomplete relief and side effects.
  • The review focuses on mechanistic links, indicating how microbial metabolites and immune responses influence depression severity.
  • Future research on multiomics profiling and AI-driven patient stratification is crucial for integrating probiotics into depression treatment.

Cite This Study

Yifan Wang (2025) studied this question.

synapsesocial.com/papers/68af4cd3ad7bf08b1ead604ahttps://doi.org/10.54254/2753-8818/2025.ld26074
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