Analysis reveals higher severe maternal morbidity and mortality rates in delivery for patients with cardiovascular disease, suggesting urgent care needs.
( Obstet Gynecol . 2025;145:e1–e10. DOI: 10.1097/AOG.0000000000005780) This study evaluated the risks of severe maternal morbidity (SMM) and death during delivery hospitalization among individuals with cardiovascular disease (CVD) using national US data from 2010 to 2020. Analyzing over 38 million delivery hospitalizations from the National Inpatient Sample, researchers found that 0.5% of patients had pre-existing CVD. These individuals experienced significantly higher rates of SMM (11.6% vs. 0.7%) and maternal mortality (538 vs. 5 per 100,000) compared to those without CVD, with an adjusted odds ratio (aOR) of 12.5 for SMM and 44.1 for maternal death.
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Toledo et al. (2025) studied this question.
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