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August 20, 2025Open Access

From Snapshots to Structure: A Novel Method for Reconstructing Directed Microbial Interaction Networks from Compositional Data

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Authors

NRN. Rajasekar

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Overview

New framework infers directed microbial interactions in communities, suggesting ecological roles and dynamics.

Key Points

  • The novel framework infers directed interactions from cross-sectional data without relying on time-series.
  • Key evidence includes identified keystone initiators and high-connectivity hubs within microbial networks.
  • Utilizing asymmetric slopes in a perturbation-informed strategy enables tracking ecological dependencies.
  • This method may enhance analysis of microbial communities, guiding microbiome engineering and public repository studies.

Cite This Study

N. Rajasekar (2025) studied this question.

synapsesocial.com/papers/68af4cdfad7bf08b1ead6654https://doi.org/10.1101/2025.08.16.670688
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