Zwitterionic Dual-Network Hydrogel Patch with Anti-Inflammatory Property for Efficient Peritoneal Adhesion Prevention

Yangrui Du; Li Ma; Shiying Lang; Shan Liu; Kang Dai; Kaijun Li; Qian Wang; Gongyan Liu

doi:10.1039/d5tb01786f

January 1, 2025Journal of Materials Chemistry B

Zwitterionic Dual-Network Hydrogel Patch with Anti-Inflammatory Property for Efficient Peritoneal Adhesion Prevention

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Key Points

The dual-network hydrogel patch reduces peritoneal adhesion, promoting better post-surgical outcomes.
Key evidence shows significant reduction of adhesion in animal models following surgery.
Development involved a zwitterionic hydrogel formulation designed for enhanced anti-inflammatory effects.
The findings imply a promising approach that may improve patient recovery post-abdominal surgery.

Implication

Dual-network hydrogel patch reduces peritoneal adhesion in abdominal surgeries, suggesting an effective solution.

Abstract

Postoperative peritoneal adhesion, driven by inflammatory response and fibrotic deposition, remains the most common complication following abdominal surgeries, with limited effective solutions. Herein, a dual-network hydrogel patch (GPSB) is developed...

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Cite This Study

Du et al. (2025) studied this question.

synapsesocial.com/papers/68af4ce5ad7bf08b1ead69c5 https://doi.org/10.1039/d5tb01786f

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Zwitterionic Dual-Network Hydrogel Patch with Anti-Inflammatory Property for Efficient Peritoneal Adhesion Prevention

Key Points

Implication

Abstract

Discussion

Cite This Study

Zwitterionic Dual-Network Hydrogel Patch with Anti-Inflammatory Property for Efficient Peritoneal Adhesion Prevention

Key Points

Implication

Abstract

Discussion

Cite This Study

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