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August 20, 2025South Asian Journal of Research in MicrobiologyOpen Access

Fabrication and Characterization of Silver Nanoparticles Produced by the Supernatant of Lactobacillus gasseri and Evaluation of their Potential Biomedical Activity

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Authors

KNK NihalaBioscience ResearchMMManeesha S. MohanPennsylvania State UniversityPSP SeenaEngineering Arts (United States)

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Implication

Experimental analysis reveals silver nanoparticles exhibit antimicrobial and anti-biofilm activity, indicating potential in medical use.

Key Points

  • Synthesis of silver nanoparticles using lactobacillus gasseri exhibited biofilm inhibition, with a peak effect at 50 µg/mL.
  • Characterization confirmed spherical nanoparticles between 60 to 140 nm, demonstrating properties suitable for biomedical use.
  • Cytotoxicity evaluated through the MTT assay showed mild reduction in cell viability, ranging from 11.26% to 19.56% across varying concentrations.
  • The findings suggest biosynthesized silver nanoparticles can be effective and biocompatible, emphasizing the need for further optimization.

Cite This Study

Nihala et al. (2025) studied this question.

synapsesocial.com/papers/68af4ce5ad7bf08b1ead6c3dhttps://doi.org/10.9734/sajrm/2025/v19i8459
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Also Consider

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