Case report reveals abnormal 131I uptake in talus, implying advanced papillary thyroid cancer with anaplastic transformation.
Talus metastasis is rarely observed on a 131 I whole-body scan (WBS). We report a case of abnormal 131 I uptake in the talus on the post-therapeutic WBS in a 54-year-old woman with papillary thyroid cancer (PTC). The patient received 2 courses of radioactive 131 I therapy (RAIT) after the thyroid surgery. WBS after the second dose of RAIT showed that 131 I uptake in the right talus declined than the last post-therapeutic WBS presented. The talus lesion was confirmed to be metastatic PTC with anaplastic transformation by pathologic examination and immunohistochemistry.
No takes yet. Share an insight, caveat, or question.
Wang et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: