This review reveals significant diagnostic challenges of neoplastic masquerade syndromes, indicating the importance of multidisciplinary approaches.
Ocular neoplastic masquerade syndromes in adults pose a significant diagnostic challenge, as intraocular malignancies can closely mimic inflammatory ocular diseases. This review focuses on intraocular lymphoma, including vitreoretinal lymphoma and uveal lymphoma, and on choroidal metastases. It provides a comprehensive overview of disease epidemiology, symptoms, clinical manifestations, imaging findings, diagnostic approach, the role of ancillary testing, and current management strategies. The importance of a multidisciplinary approach is emphasized. This review aims to provide clinicians with practical tools for diagnosing and managing neoplastic masquerade syndromes.
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Habot-Wilner et al. (2025) studied this question.
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