Prospective analysis revealed buffered lidocaine improves injection comfort and rapid anaesthesia onset in mandibular extractions, suggesting effective local anaesthetic options.
A BSTRACT Background: This prospective study was conducted to evaluate and compare the effectiveness of two local anaesthetic solutions: 4% articaine and buffered 2% lidocaine used during mandibular third molar extractions. Materials and Methods: A total of 200 extractions were performed at Sri Aurobindo College of Dentistry, equally divided into two groups. Results and Conclusion: Buffered Lidocaine was associated with reduced pain during injection and faster onset of subjective anaesthesia, whereas Articaine provided better pain control during the procedure. Both anaesthetics showed comparable durations and no postoperative complications, indicating both are safe and effective options when used appropriately.
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Agrawal et al. (2025) studied this question.
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