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HPV‐Vaccine and Reduced Odds Ratio for Oral and Oropharyngeal Cancer in Both Genders

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Analysis reveals HPV vaccination lowers oral and oropharyngeal cancer odds in both males and females, suggesting preventive potential.

The HPV vaccine is linked to a significantly reduced odds ratio for oral and oropharyngeal cancer, especially in vaccinated individuals.
Vaccinated individuals had an odds ratio of 0.008 for oral/oropharyngeal cancer, markedly lower than non-vaccinated counterparts.
Data were drawn from a cohort of over 1.7 million patients at the University of Florida between 2015 and 2022, focusing on cancer types associated with HPV.
Results indicate that HPV vaccination significantly lowers cancer risk, emphasizing the need for public health initiatives around vaccination.

Katz et al. (2025) studied this question.

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