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August 21, 2025Journal of Complementary and Integrative Medicine

Teratogenic effect of unregistered traditional Chinese medicine containing Atractylodis lancea radix, Glycyrrhiza glabra radix, Rheum officinale rhizome, and Angelica dahurica radix on fetal morphology of BALB/c mice

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Substantial differences in maternal and fetal body weight were observed in all treatment groups.
Increased skeletal abnormalities were noted in fetuses exposed to higher doses of traditional Chinese medicine (p<0.05).
Laparotomy revealed open eyelid and clubfoot abnormalities, along with severe hemorrhages in fetuses from the highest dose group.
The study indicates that unregistered traditional Chinese medicine can affect fetal development at critical stages during pregnancy.

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Implication

This research uncovers the teratogenic effects of traditional Chinese medicine on fetal morphology in pregnant BALB/c mice, suggesting potential risks during pregnancy.

Cite This Study

Rachmaini et al. (2025) studied this question.

synapsesocial.com/papers/68af5210ad7bf08b1ead9728 https://doi.org/10.1515/jcim-2025-0073

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Implication

This research uncovers the teratogenic effects of traditional Chinese medicine on fetal morphology in pregnant BALB/c mice, suggesting potential risks during pregnancy.

Teratogenic effect of unregistered traditional Chinese medicine containing Atractylodis lancea radix, Glycyrrhiza glabra radix, Rheum officinale rhizome, and Angelica dahurica radix on fetal morphology of BALB/c mice

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Discussion

Implication

Cite This Study

Teratogenic effect of unregistered traditional Chinese medicine containing Atractylodis lancea radix, Glycyrrhiza glabra radix, Rheum officinale rhizome, and Angelica dahurica radix on fetal morphology of BALB/c mice

Key Points

Discussion

Implication

Cite This Study

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