Comparison of Nebulized Versus Systemic Corticosteroid for Management of Children Presenting with Acute Exacerbation of Asthma

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Discussion

Randomized trial finds systemic corticosteroids improve asthma symptoms faster in children, indicating stronger management efficacy.

Systemic corticosteroids resulted in a 17% higher rate of symptom resolution compared to nebulized corticosteroids at 48 hours, suggesting greater efficiency.
The Pediatric Asthma Severity Score (PASS) indicated similar baseline asthma severity between the two groups, highlighting the effectiveness of both treatments.
Conducted as a randomized controlled trial with 240 participants aged 2 to 12, providing robust data for treatment comparison.
The findings emphasize the need for timely intervention in acute pediatric asthma cases, potentially enhancing treatment protocols.

Ahmad et al. (2025) studied this question.

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